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Lilly Acquires Asahi Kasei’s Chronic Pain Candidate

To pay $20 million upfront and up to $210 million in potential milestones for AK1780, an orally bioavailable P2X7 receptor antagonist.

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By: Kristin Brooks

Managing Editor, Contract Pharma

Eli Lilly and Co. and Asahi Kasei Pharma entered a license agreement under which Lilly will acquire the exclusive rights for AK1780 from Asahi Kasei Pharma. AK1780 is an orally bioavailable P2X7 receptor antagonist that recently completed Phase 1 dose and clinical pharmacology studies. P2X7 receptors are implicated in neuroinflammation, a driving force in chronic pain conditions.   Lilly will be responsible for future global development and regulatory activities for AK1780. Lilly will pay $20 ...

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